MISSINGNESS ADAPTED GROUP INFORMED CLUSTERED (MAGIC)-LASSO: A NOVEL PARADIGM FOR PHENOTYPE PREDICTION TO IMPROVE POWER FOR GENETIC LOCI DISCOVERY

Missingness adapted group informed clustered (MAGIC)-LASSO: a novel paradigm for phenotype prediction to improve power for genetic loci discovery

Introduction: The availability of large-scale biobanks linking genetic data, rich phenotypes, and biological measures is a powerful opportunity for scientific discovery.However, real-world collections frequently have extensive missingness.While missing data prediction is possible, performance is significantly impaired by block-wise missingness inhe

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